Providing an insight into the performance of Pegasus™ Prime virus filters, we show how an understanding of filtration theory influences membrane development and how this understanding results novel features that deliver throughput improvements and robust virus reduction. To learn more about Pegasus Prime virus filters go to https://shop.pall.com/us/en/biotech/pall-microdisc-capsules-with-pegasus-prime-virus-removal-filter-membrane-zidiqdrt4mk